I talk alot about using vaginal estrogen to support your mucosal lining. And I recommend Bi-Est, the two kinds of estrogen: Estriol and Estradiol. They are so protective.
Vagina Estrogen is also helpful in over 50% of women who have recurring urinary tract infections.*
Low estrogen levels affect the vaginal and bladder microbiomes, reduce blood flow to the bladder and urethra, and make urethral cells more fragile, which can allow bacteria to attach more easily.
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I recommend my friend Dr. Michelle Sand’s Glow Below. The estrogen version has Bi-Est in it. The DHEA version is estrogen-free and increases sensation and suppleness.
If you get recurrent UTI’s and you’re on antibiotics a lot, consider a D-Mannose alternative. It’s easier on your gut and 90+% of UTI’s are e Coli driven.
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*References
Risto Ikähelmo, Anja Siitonen, Tarja Heiskanen, Ulla Kärkkäinen, Pauli Kuosmanen, Pertti Lipponen, P. Helena Mäkelä, Recurrence of Urinary Tract Infection in a Primary Care Setting: Analysis of a I-Year Follow-up of 179 Women, Clinical Infectious Diseases, Volume 22, Issue 1, January 1996, Pages 91–99, https://doi.org/10.1093/clinids/22.1.91
Vazquez-Montes MDLA, Fanshawe TR, Stoesser N, Walker AS, Butler C, Hayward G. Epidemiology and microbiology of recurrent UTI in women in the community in Oxfordshire, UK. JAC Antimicrob Resist. 2024 Jan 10;6(1):dlad156. doi: 10.1093/jacamr/dlad156. PMID: 38204597; PMCID: PMC10781434.
Raz R, Stamm WE. A controlled trial of intravaginal estriol in postmenopausal women with recurrent urinary tract infections. N Engl J Med. 1993 Sep 9;329(11):753-6. doi: 10.1056/NEJM199309093291102. PMID: 8350884.
Ferrante KL, Wasenda EJ, Jung CE, Adams-Piper ER, Lukacz ES. Vaginal Estrogen for the Prevention of Recurrent Urinary Tract Infection in Postmenopausal Women: A Randomized Clinical Trial. Female Pelvic Med Reconstr Surg. 2021 Feb 1;27(2):112-117. doi: 10.1097/SPV.0000000000000749. PMID: 31232721.
67Perrotta C, Aznar M, Mejia R, et al. Oestrogens for preventing recurrent urinary tract infection in postmenopausal women. Cochrane Database Syst Rev 2008;(2): CD005131.
Chen YY, Su TH, Lau HH. Estrogen for the prevention of recurrent urinary tract infections in postmenopausal women: a meta-analysis of randomized controlled trials. Int Urogynecol J. 2021 Jan;32(1):17-25. doi: 10.1007/s00192-020-04397-z. Epub 2020 Jun 20. PMID: 32564121.
Erikson B. A randomized, open, parallel-group study on the preventive effect of an estradiol-releasing vaginal ring (Estring) on recurrent urinary tract infections in postmenopausal women. Am J obstet Gynecol 1999; 180: 1072-1079.